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alpha 1 Antichymotrypsin / AACT Monoclonal Antibody
Cat.No:EPM12137
Price: Inquire
Immunogen: alpha 1 Antichymotrypsin / AACT fusion protein ag2830
Synonym:
A1 Antichymotrypsin, AACT, ACT, Alpha 1 antichymotrypsin, GIG24, GIG25, Serpin A3, SERPINA3
Calculated MW: 448aa,48 kDa
Observed MW: 65 kDa
Source:
Mouse
Isotype:
IgG2b
Reactivity: H;

Clonality: Monoclonal


Application:
ELISA,WB,IHC
Purify:
Protein A purification
Concentration:
Storage Buffer:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage:
Store at -20℃. Avoid freeze / thaw cycles.
alpha 1 Antichymotrypsin / AACT Monoclonal Antibody
human blood tissue were subjected to SDS PAGE followed by western blot with SERPINA3,AACT antibody at dilution of 1:1000
Protocols:
Background:
Human SerpinA3, also known as Alpha 1-antichymotrypsin (AACT), is a member of the serine protease inhibitor class, and is a plasma alpha globulin glycoprotein which increases in the blood during the inflammatory process. SerpinA3, is also an inhibitor of neutrophil cathepsin G, mast cell chymases and pancreatic chymotrypsin. SerpinA3 is produced primarily in the liver, and is identified as an acute-phase inflammatory protein. SerpinA3 deficiency has been associated with liver disease. SerpinA3 has also been implicated in the pathology of a number of devastating human diseases including chronic obstructive pulmonary disease (COPD), Parkinson’s disease (PD), Alzheimer’s disease (AD), Stroke, Cystic Fibrosis, Cerebral Haemorrhage and Multiple System Atrophy.
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