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Amyloid beta (A4) precursor protein Monoclonal Antibody
Cat.No:EPM12144
Price: Inquire
Immunogen: Amyloid beta (A4) precursor protein fusion protein ag0769
Synonym:
A4, AAA, ABETA, ABPP, AD1, AICD 50, AICD 57, AICD 59, AID(50), AID(57), AID(59), Amyloid beta A4 protein, amyloid P, APP, APPI, beta Amyloid, CTFgamma, CVAP, Gamma CTF(50) C31, PN II, PN2, PreA4, Protease nexin II, S APP alpha Soluble APP beta
Calculated MW: 86.9 kDa
Observed MW: 100 kDa
Source:
Mouse
Isotype:
IgG2a
Reactivity: H,Pg;

Clonality: Monoclonal


Application:
ELISA,WB,IHC
Purify:
Protein A purification
Concentration:
Storage Buffer:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage:
Store at -20℃. Avoid freeze / thaw cycles.
Amyloid beta (A4) precursor protein Monoclonal Antibody
Y79 cells were subjected to SDS PAGE followed by western blot with APP antibody at dilution of 1:1000
Protocols:
Background:
Aβ derives from APP via proteolytic cleavage by proteases called α-, β- and γ-secretase. The α-secretase cleavage precludes the formation of Aβ, while the β- and γ-cleavages generate APP components with amyloidogenic features. Amyloid beta A4 precursor protein(APP), encoded by APP gene which locate on human chromosome 21q, is a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. APP expressed in all fetal tissues and is pronounced in brain, kidney, heart and spleen, but weak in liver. Defects in APP are the cause of Alzheimer disease type 1 (AD1).
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