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Angiotensinogen Monoclonal Antibody
Cat.No:EPM12145
Price: Inquire
Immunogen: Angiotensinogen fusion protein ag2632
Synonym:
AGT, Ang I Angiotensin 2, Ang II Angiotensin 3, Ang III, Angiotensin I, Angiotensin II, Angiotensin III, Angiotensinogen, ANHU, Des Asp[1] angiotensin II, FLJ92595, FLJ97926, Serpin A8, SERPINA8
Calculated MW: 485aa,53 kDa
Observed MW: 52 kDa
Source:
Mouse
Isotype:
IgG2b
Reactivity: H;

Clonality: Monoclonal


Application:
ELISA,WB,IHC
Purify:
Protein A purification
Concentration:
Storage Buffer:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Storage:
Store at -20℃. Avoid freeze / thaw cycles.
Angiotensinogen Monoclonal Antibody
HepG2 cells were subjected to SDS PAGE followed by western blot with AGT antibody at dilution of 1:1000
Protocols:
Background:
Angiotensinogen is a precursor of angiotensin II (Ang II), is expressed and synthesized largely in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. It has a key role in mediating vascular constriction and regulating salt and fluid homeostasis. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.
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